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Assay Detail

CHEMBL5622003

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to wild type tubulin (unknown origin) by MST analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Tubulin (CHEMBL2095182)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy.
Liu X, Jin J, Wu Y, Du B, Zhang L, Lu D, Liu Y, Chen X, Lin J, Chen H, Zhang W, Zhuang C, Luan X.
Eur J Med Chem (2023) 257 : 115540 -115540
PubMed 37301075 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.87 6.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5630413 1 6.87

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5630413 Kd = 136.0 nM 6.87