Assay Detail
Functional
CHEMBL5622877
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Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability measured after 72 hrs by Alamar blue assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RS4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A platform for the rapid synthesis of molecular glues (Rapid-Glue) under miniaturized conditions for direct biological screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 8.43 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4742712 | — | — | 1 | 10.00 |
| CHEMBL5630891 | — | — | 1 | 8.70 |
| CHEMBL5631072 | — | — | 1 | 8.15 |
| CHEMBL5630057 | — | — | 1 | 8.15 |
| CHEMBL5630340 | — | — | 1 | 7.15 |
| CHEMBL5625016 | — | — | 1 | - |
| CHEMBL5624845 | — | — | 1 | - |
| CHEMBL5630636 | — | — | 1 | - |
| CHEMBL5624467 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4742712 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL5630891 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5631072 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5630057 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL5630340 | — | IC50 | = | 71.0 | nM | 7.15 |
| CHEMBL5625016 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5624845 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5630636 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5624467 | — | IC50 | > | 1000.0 | nM | - |