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Assay Detail

CHEMBL5623957

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against TEL-BMX transformed mouse BaF3 cells assessed as inhibition of cell proliferation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type BaF3
Confidence 1 — Organism
Curated By Autocuration

Target

BaF3 (CHEMBL614524)
Type CELL-LINE
Organism Mus musculus

Publication

2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling.
Shaldam MA, Hendrychová D, El-Haggar R, Vojáčková V, Majrashi TA, Elkaeed EB, Masurier N, Kryštof V, Tawfik HO, Eldehna WM.
Eur J Med Chem (2023) 258 : 115610 -115610
PubMed 37437350 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.60 7.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4091991 1 7.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4091991 IC50 = 25.0 nM 7.60