Assay Detail
Functional
CHEMBL5625303
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anticancer activity against human TF-1 cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TF-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Challenges for the development of mutant isocitrate dehydrogenases 1 inhibitors to treat glioma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.54 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4651002 | SAFUSIDENIB | 2.0 | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4651002 | SAFUSIDENIB | IC50 | = | 29.0 | nM | 7.54 |