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Assay Detail

CHEMBL5626278

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]17 beta estradiol from human ERbeta by radioligand binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Estrogen receptor beta (CHEMBL242)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advance of small-molecule drugs for clinical treatment of osteoporosis: A review.
Zhang JY, Zhong YH, Chen LM, Zhuo XL, Zhao LJ, Wang YT.
Eur J Med Chem (2023) 259 : 115654 -115654
PubMed 37467618 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46740 BAZEDOXIFENE 4.0 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46740 BAZEDOXIFENE IC50 = 99.0 nM 7.00