Assay Detail
Binding
CHEMBL5628546
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant HDAC7 (unknown origin) using trifluoroacetyl lysine as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.44 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5631614 | — | — | 1 | 7.51 |
| CHEMBL3110004 | — | — | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5631614 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL3110004 | — | IC50 | = | 44.0 | nM | 7.36 |