Assay Detail
Binding
CHEMBL5628828
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC7 (unknown origin) using boc-(trifluoroacetyl)lysineAMC as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescent based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational discovery of dual FLT3/HDAC inhibitors as a potential AML therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.18 | 7.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3110004 | — | — | 1 | 7.18 |
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3110004 | — | IC50 | = | 66.6 | nM | 7.18 |
| CHEMBL99 | TRICHOSTATIN | IC50 | - | — | - |