Assay Detail
Functional
CHEMBL5634330
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus (CHEMBL613758) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus |
Publication
Fluorine in anti-HIV drugs approved by FDA from 1981 to 2023.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.76 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222559 | TIPRANAVIR | 4.0 | 1 | 7.52 |
| CHEMBL1465 | PHENPROCOUMON | 4.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222559 | TIPRANAVIR | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1465 | PHENPROCOUMON | IC50 | = | 100000.0 | nM | 4.00 |