Assay Detail
Functional
CHEMBL5634348
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity HIV-1 infected in HEK293T cells assessed as inhibition of late stage viral replication
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | HEK293T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Fluorine in anti-HIV drugs approved by FDA from 1981 to 2023.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.50 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4594438 | LENACAPAVIR | 4.0 | 1 | 9.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4594438 | LENACAPAVIR | IC50 | = | 0.314 | nM | 9.50 |