Assay Detail
Binding
CHEMBL5634575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Tyrosine kinase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Catechol-mimicking transition-state analogues as non-oxidizable inhibitors of tyrosinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.80 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5280416 | — | — | 1 | 5.44 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.51 |
| CHEMBL481194 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5280416 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL481194 | — | IC50 | = | 36000.0 | nM | 4.44 |