Assay Detail
Binding
CHEMBL5634583
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Binding affinity to Mushroom Tyrosinase assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Catechol-mimicking transition-state analogues as non-oxidizable inhibitors of tyrosinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.12 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5646548 | — | — | 1 | 5.40 |
| CHEMBL245416 | L-MIMOSINE | — | 1 | 5.10 |
| CHEMBL121471 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5646548 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL245416 | L-MIMOSINE | Ki | = | 8000.0 | nM | 5.10 |
| CHEMBL121471 | — | Ki | = | 14000.0 | nM | 4.85 |