Assay Detail
Binding
CHEMBL5634724
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SOS1/KRAS (unknown origin) protein-protein interaction by alpha screen assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Recent advances in the development of inhibitors targeting KRAS-G12C and its related pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4519023 | — | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4519023 | — | IC50 | = | 4.0 | nM | 8.40 |