Assay Detail
Binding
CHEMBL5634868
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells incubated for 30 mins in presence of [gamma32P]ATP by scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small molecule inhibitors of NLRP3 inflammasome and GSK-3β in the management of traumatic brain injury: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL336961 | AZAKENPAULLONE | — | 1 | 8.40 |
| CHEMBL5639224 | — | — | 1 | 8.40 |
| CHEMBL296586 | KENPAULLONE | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL336961 | AZAKENPAULLONE | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL5639224 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL296586 | KENPAULLONE | IC50 | = | 4.0 | nM | 8.40 |