Assay Detail
Binding
CHEMBL5648066
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KDM5B (1 to 809 residues)(unknown origin) by Alphalisa assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of demethylases by GSK-J1/J4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.42 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3188597 | — | — | 1 | 6.77 |
| CHEMBL3183531 | — | — | 1 | 5.01 |
| CHEMBL4303308 | — | — | 1 | 4.48 |
| CHEMBL4786329 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3188597 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL3183531 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL4303308 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL4786329 | — | IC50 | > | 25000.0 | nM | - |