Assay Detail
Binding
CHEMBL5652955
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human PLEKHG3 incubated for 45 mins by Kinobead based pull down assay
2
Total Activities
1
Compounds Tested
2
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Pleckstrin homology domain-containing family G member 3 (CHEMBL6066528) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.50 | 9.50 |
| ED50 | 1 | 8.26 | 8.26 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | MONDO:0004992 |
| EFO_TERM | EFO_TERM | - | — | cancer |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752910 | — | — | 2 | 9.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752910 | — | Kd | = | 0.315 | nM | 9.50 |
| CHEMBL3752910 | — | ED50 | = | 5.534 | nM | 8.26 |