Assay Detail
Binding
CHEMBL5653821
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of purified ErbB1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
CI-1033, an irreversible pan-erbB receptor inhibitor and its potential application for the treatment of breast cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.10 | 9.10 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | MONDO:0007254 |
| EFO_TERM | EFO_TERM | - | — | breast cancer |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL545315 | CANERTINIB DIHYDROCHLORIDE | 3.0 | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL545315 | CANERTINIB DIHYDROCHLORIDE | IC50 | = | 0.8 | nM | 9.10 |