Assay Detail
Binding
CHEMBL5713112
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of biotinylated tetra-acetylated histone H4 (1 to 21) peptide from His6-tagged BRD2 (1 to 473 residues) (unknown origin) expressed in Escherichia coli measured after 1 hr by TR-FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1950956 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1950956 | — | IC50 | = | 2000.0 | nM | 5.70 |