Assay Detail
Binding
CHEMBL5713480
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by bromoKdselect analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Chromatin remodeling regulator CECR2 (CHEMBL3108639) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.00 | 9.00 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | EFO:0000222 |
| EFO_ID | EFO_ID | - | — | EFO:0000222 |
| EFO_TERM | EFO_TERM | - | — | acute myeloid leukemia |
| EFO_TERM | EFO_TERM | - | — | acute myeloid leukemia |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3823478 | — | — | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3823478 | — | Kd | = | 1.0 | nM | 9.00 |