Assay Detail
Binding
CHEMBL5720948
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3K alpha (unknown origin) by drug competition for substrate binding based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (CHEMBL4005) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of Human Class I vs Class III Phosphatidylinositol 3'-Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.47 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1765602 | — | — | 1 | 8.33 |
| CHEMBL5723005 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1765602 | — | EC50 | = | 4.68 | nM | 8.33 |
| CHEMBL5723005 | — | EC50 | = | 250.0 | nM | 6.60 |