Assay Detail
Binding
CHEMBL5720955
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3K alpha (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (CHEMBL4005) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of Human Class I vs Class III Phosphatidylinositol 3'-Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.40 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3218578 | BGT-226 FREE BASE | 2.0 | 1 | 8.40 |
| CHEMBL3622372 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3218578 | BGT-226 FREE BASE | EC50 | = | 4.0 | nM | 8.40 |
| CHEMBL3622372 | — | EC50 | > | 10000.0 | nM | - |