Assay Detail
Functional
CHEMBL5723054
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Affinity Biochemical interaction: (inhibition of methyl group transfer to biotin-labelled peptide using [3H]S-5'-adenosyl-L-methionine (SAM) as the methyl donor, scintillation proximity assay) EUB0000034d PRMT8
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | Affinity biochemical assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein arginine N-methyltransferase 8 (CHEMBL3108648) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Affinity Biochemical Literature for EUbOPEN Chemogenomic Library
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.89 | 8.89 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Mode of action | Mode of action | - | — | Inhibitor |
| Protein family | Protein family | - | — | HMT |
| Recommended concentration | Recommended concentration | 1.0 | uM | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3901808 | — | — | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3901808 | — | Ki | = | 1.3 | nM | 8.89 |