Protein arginine N-methyltransferase 8 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9NR22. Use UniProt Q9NR22 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9NR22 as the stable identity anchor, then attach disease evidence before program review.
Protein arginine N-methyltransferase 8
Review this target as Protein arginine N-methyltransferase 8, mapped to UniProt Q9NR22. Sequence length is 394 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein arginine N-methyltransferase 8 as ChEMBL target CHEMBL3108648, mapped to UniProt Q9NR22. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein arginine N-methyltransferase 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NR22 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein arginine N-methyltransferase 8 |
| UniProt Accession | Q9NR22 |
| Component Type | Protein |
| Sequence Length | 394 aa |
Protein arginine N-methyltransferase 8
Review this target as Protein arginine N-methyltransferase 8, mapped to UniProt Q9NR22. Sequence length is 394 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4094513 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL3901808 | 8.89 | Ki | 1.3 | Preclinical |
| CHEMBL5559689 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL3589029 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5723346 | 8.7 | Ki | 2.0 | Preclinical |
| CHEMBL5723346 | 8.41 | IC50 | 3.9 | Preclinical |
| CHEMBL3901808 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5633822 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3589030 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL3589026 | 8.0 | IC50 | 10.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 79 | 42 | 6.4 |
| assay format | 8 | 29 | 6.7 |
| cell-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 2 | 8.6 |
| cell-based format | 1 | 0 | — |