Assay Detail

CHEMBL5723091

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Functional

Affinity Biochemical interaction: (enzymatic assay (fluorogenic substrate cleavage)) EUB0002173aAD CASP3

ChEMBL ↗

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Target

Caspase-3 (CHEMBL2334) ↗

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Primary target Caspase-3

CHEMBL2334

Anchored from Assay target.

Protein identity Caspase-3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Category	Affinity biochemical assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Caspase-3 (CHEMBL2334) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Affinity Biochemical Literature for EUbOPEN Chemogenomic Library

EUbOPEN
(2024)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	9.64	9.64

Assay Parameters

Parameter	Type	Value	Units	Text
Mode of action	Mode of action	-	—	Inhibitor
Recommended concentration	Recommended concentration	1.0	uM	—

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5723373	—	—	1	9.64

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5723373	—	Ki	=	0.23	nM	9.64