Assay Detail
Functional
CHEMBL5723544
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Affinity On-target Cellular interaction: (Inhibition of uridine influx (10 uM) measured in oocytes injected with R transcript for human SLC29A1) EUB0002708a SLC29A1
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Oocyte |
| Category | Affinity on-target cellular assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Equilibrative nucleoside transporter 1 (CHEMBL1997) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Affinity On-target Cellular Literature for EUbOPEN Chemogenomic Library
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.44 | 8.44 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Mode of action | Mode of action | - | — | Inhibitor |
| Protein family | Protein family | - | — | SLC |
| Recommended concentration | Recommended concentration | 1.0 | uM | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418509 | NITROBENZYLMERCAPTOPURINE RIBONUCLEOSIDE | — | 1 | 8.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418509 | NITROBENZYLMERCAPTOPURINE RIBONUCLEOSIDE | IC50 | = | 3.6 | nM | 8.44 |