Assay Detail
Functional
CHEMBL5724430
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antigen challenge cell assay ( Based on the use of B cells to “present” exogenous antigen (added ovalbumin) via a cathepsin S dependent process to T cells.)
1
Total Activities
1
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BI-1915
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.55 | 8.55 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Based on the use of B cells to “present” exogenous antigen (added ovalbumin) via a cathepsin S dependent process to T cells. |
| Assay publication | Assay publication | - | — | PMID: 23084902 (supplement) |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2207559 | — | — | 1 | 8.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2207559 | — | IC50 | = | 2.8 | nM | 8.55 |