Assay Detail
Binding
CHEMBL5736263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Kinase Activity: Compounds of the invention were assayed for activity against a variety of different kinases.
3
Total Activities
1
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Homeodomain-interacting protein kinase 4 (CHEMBL1075167) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibitors of cyclin-dependent kinase 7 (CDK7)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.26 | 6.26 |
| kon | 1 | - | - |
| k_off | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4434871 | — | — | 3 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4434871 | — | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL4434871 | — | kon | = | - | — | - |
| CHEMBL4434871 | — | k_off | = | - | s-1 | - |