Assay Detail
Binding
CHEMBL615265
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 5'-inosine monophosphate dehydrogenase type I (IMPDH I)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Inosine-5'-monophosphate dehydrogenase 1 (CHEMBL1822) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.80 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23716 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23716 | — | IC50 | = | 160.0 | nM | 6.80 |