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Assay Detail

CHEMBL615302

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Binding
Binding affinity for 3-beta-hydroxysteroid dehydrogenase
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Publication

Pharmacological options in the treatment of benign prostatic hyperplasia.
Kenny B, Ballard S, Blagg J, Fox D.
J Med Chem (1997) 40 : 1293 -1315
PubMed 9135028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 13 6.84 8.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL25516 1 8.11
CHEMBL280155 1 8.00
CHEMBL297524 1 7.92
CHEMBL25183 1 7.72
CHEMBL24088 1 6.82
CHEMBL283123 1 6.80
CHEMBL3085538 1 6.75
CHEMBL24291 1 6.72
CHEMBL282037 1 6.72
CHEMBL283430 1 6.31
CHEMBL412425 1 6.29
CHEMBL277224 1 5.80
CHEMBL710 FINASTERIDE 4.0 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL25516 Ki = 7.8 nM 8.11
CHEMBL280155 Ki = 10.0 nM 8.00
CHEMBL297524 Ki = 12.0 nM 7.92
CHEMBL25183 Ki = 19.0 nM 7.72
CHEMBL24088 Ki = 150.0 nM 6.82
CHEMBL283123 Ki = 160.0 nM 6.80
CHEMBL3085538 Ki = 180.0 nM 6.75
CHEMBL24291 Ki = 190.0 nM 6.72
CHEMBL282037 Ki = 190.0 nM 6.72
CHEMBL283430 Ki = 490.0 nM 6.31
CHEMBL412425 Ki = 510.0 nM 6.29
CHEMBL277224 Ki = 1600.0 nM 5.80
CHEMBL710 FINASTERIDE Ki = 11000.0 nM 4.96