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Assay Detail

CHEMBL615509

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration required to stimulate glucose uptake in 3T3-L1 adipocytes after 48 hr incubation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type 3T3-L1
Confidence 1 — Organism
Curated By Intermediate

Target

3T3-L1 (CHEMBL614510)
Type CELL-LINE
Organism Mus musculus

Publication

Hypoglycemic activity of a series of alpha-alkylthio and alpha-alkoxy carboxylic acids related to ciglitazone.
Hulin B, Newton LS, Lewis DM, Genereux PE, Gibbs EM, Clark DA.
J Med Chem (1996) 39 : 3897 -3907
PubMed 8831756 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL435405 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL435405 EC50 = 10.0 nM 8.00