Compound Detail
CHEMBL435405
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Basic Information
| ChEMBL ID | CHEMBL435405 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZWZFFTHXSRRHOU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
191.2
MW (Da)
1.17
ALogP
3
HBA
0
HBD
46.6
PSA (Ų)
0.70
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3T3-L1 CHEMBL614510 | EC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3T3-L1 | EC50 | = | 10.0 | nM | 8.0 | Concentration required to stimulate glucose uptake in 3T3-L1 adipocytes after 48... | 8831756 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8831756 | 10.1021/jm960230h | 3T3-L1 | 1 |
Data from ChEMBL 36 via Core Engine