Assay Detail
Functional
CHEMBL615603
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Cytotoxic effect on 3T3 cells
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.69 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL411 | DIETHYLSTILBESTROL | 4.0 | 1 | 5.60 |
| CHEMBL47966 | — | — | 1 | 5.26 |
| CHEMBL295539 | — | — | 1 | 5.22 |
| CHEMBL44227 | — | — | 1 | 4.96 |
| CHEMBL48033 | — | — | 1 | 4.87 |
| CHEMBL45564 | — | — | 1 | 4.70 |
| CHEMBL43722 | — | — | 1 | 4.60 |
| CHEMBL44326 | — | — | 1 | 4.52 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 4.40 |
| CHEMBL48085 | — | — | 1 | 4.33 |
| CHEMBL46786 | — | — | 1 | 4.25 |
| CHEMBL47875 | — | — | 1 | 4.15 |
| CHEMBL47361 | — | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL411 | DIETHYLSTILBESTROL | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL47966 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL295539 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL44227 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL48033 | — | IC50 | = | 13500.0 | nM | 4.87 |
| CHEMBL45564 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL43722 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL44326 | — | IC50 | = | 30500.0 | nM | 4.52 |
| CHEMBL50 | QUERCETIN | IC50 | = | 39500.0 | nM | 4.40 |
| CHEMBL48085 | — | IC50 | = | 47000.0 | nM | 4.33 |
| CHEMBL46786 | — | IC50 | = | 56500.0 | nM | 4.25 |
| CHEMBL47875 | — | IC50 | = | 71500.0 | nM | 4.15 |
| CHEMBL47361 | — | IC50 | = | 79500.0 | nM | 4.10 |