Assay Detail
Functional
CHEMBL615664
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Effect on the growth of 3LL cells was evaluated using an MTT assay at 48 hour incubation
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | 3LL |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
N-Benzylpolyamines as vectors of boron and fluorine for cancer therapy and imaging: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.92 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL540826 | — | — | 1 | 5.33 |
| CHEMBL543171 | — | — | 1 | 4.51 |
| CHEMBL123648 | SULFHYDRYL BORON HYDRIDE | — | 1 | - |
| CHEMBL2448379 | — | — | 1 | - |
| CHEMBL2448381 | — | — | 1 | - |
| CHEMBL543409 | — | — | 1 | - |
| CHEMBL2448382 | — | — | 1 | - |
| CHEMBL538032 | — | — | 1 | - |
| CHEMBL543172 | — | — | 1 | - |
| CHEMBL2448380 | — | — | 1 | - |
| CHEMBL122888 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL540826 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL543171 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL123648 | SULFHYDRYL BORON HYDRIDE | IC50 | = | 287000.0 | nM | - |
| CHEMBL2448379 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL2448381 | — | IC50 | = | 824000.0 | nM | - |
| CHEMBL543409 | — | IC50 | = | 993000.0 | nM | - |
| CHEMBL2448382 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL538032 | — | IC50 | = | 568000.0 | nM | - |
| CHEMBL543172 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL2448380 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL122888 | — | IC50 | > | 100000.0 | nM | - |