Assay Detail
Binding
CHEMBL615765
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity on human cloned 5-hydroxytryptamine 1A receptor transfected in human cell lines (He La)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Cell line |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 10.10 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL444590 | — | — | 1 | 10.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL444590 | — | Ki | = | 0.08 | nM | 10.10 |