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Assay Detail

CHEMBL615969

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Binding
In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in CHO cells (sc)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1A (CHEMBL273)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

(S)- and (R)-8-(di-n-propylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1- carbaldehyde: a new class of orally active 5-HT1A-receptor agonists.
Stjernlöf P, Gullme M, Elebring T, Andersson B, Wikström H, Lagerquist S, Svensson K, Ekman A, Carlsson A, Sundell S.
J Med Chem (1993) 36 : 2059 -2065
PubMed 8340910 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.70 9.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL304426 1 9.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL304426 Ki = 0.2 nM 9.70