Assay Detail
Functional
CHEMBL616048
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Functional characteristics of a series of N4-substituted 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazines as 5-HT1A receptor ligands. Structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.68 | 8.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1742477 | FLESINOXAN | 2.0 | 1 | 8.18 |
| CHEMBL8412 | IPSAPIRONE | 2.0 | 1 | 7.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1742477 | FLESINOXAN | EC50 | = | 6.607 | nM | 8.18 |
| CHEMBL8412 | IPSAPIRONE | EC50 | = | 67.61 | nM | 7.17 |