Assay Detail
Binding
CHEMBL616197
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in rat hippocampus membrane.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Hippocampus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Serotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.82 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL122485 | — | — | 1 | 5.94 |
| CHEMBL124419 | — | — | 1 | 5.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL122485 | — | Ki | = | 1150.0 | nM | 5.94 |
| CHEMBL124419 | — | Ki | = | 2030.0 | nM | 5.69 |