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Assay Detail

CHEMBL616234

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for its ability to displace [3H]8-OH-DPAT binding from human 5-hydroxytryptamine 1A receptor in mammalian cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1A (CHEMBL214)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor.
Kikuchi C, Nagaso H, Hiranuma T, Koyama M.
J Med Chem (1999) 42 : 533 -535
PubMed 10052959 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL69257 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL69257 Ki = 169.82 nM 6.77