Assay Detail
Binding
CHEMBL616302
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Development of fluorine-18-labeled 5-HT1A antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.26 | 9.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38413 | — | — | 1 | 9.29 |
| CHEMBL31354 | WAY-100,635 | — | 1 | 9.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38413 | — | Ki | = | 0.515 | nM | 9.29 |
| CHEMBL31354 | WAY-100,635 | Ki | = | 0.59 | nM | 9.23 |