Assay Detail
Binding
CHEMBL616391
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for binding affinity to 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as a radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of metabolically stable arylpiperazine 5-HT1A receptor agonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.78 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL49630 | — | — | 1 | 8.06 |
| CHEMBL8412 | IPSAPIRONE | 2.0 | 1 | 7.92 |
| CHEMBL48100 | — | — | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL49630 | — | Ki | = | 8.7 | nM | 8.06 |
| CHEMBL8412 | IPSAPIRONE | Ki | = | 12.1 | nM | 7.92 |
| CHEMBL48100 | — | Ki | = | 43.7 | nM | 7.36 |