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Assay Detail

CHEMBL616395

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound measured for 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT-labeled porcine brain homogenates
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Tissue Brain
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1A (CHEMBL214)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Fused azaindole derivatives: molecular design, synthesis and in vitro pharmacology leading to the preferential dopamine D3 receptor agonist FAUC 725.
Löber S, Hübner H, Gmeiner P.
Bioorg Med Chem Lett (2002) 12 : 2377 -2380
PubMed 12161137 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL310867 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL310867 Ki = 2500.0 nM 5.60