Assay Detail
Binding
CHEMBL616689
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Affinity in displacing [3H]8-OH-DPAT from rat hippocampal 5-HT1A receptor.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Hippocampus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Stereoselective LSD-like activity in d-lysergic acid amides of (R)- and (S)-2-aminobutane.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.50 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66335 | — | — | 1 | 8.70 |
| CHEMBL263881 | LYSERGIDE | 2.0 | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66335 | — | Ki | = | 2.01 | nM | 8.70 |
| CHEMBL263881 | LYSERGIDE | Ki | = | 5.05 | nM | 8.30 |