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Assay Detail

CHEMBL616698

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against rat 5-hydroxytryptamine 1A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1A (CHEMBL273)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
el Ahmad Y, Laurent E, Maillet P, Talab A, Teste JF, Dokhan R, Tran G, Ollivier R.
J Med Chem (1997) 40 : 952 -960
PubMed 9083484 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.67 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL56 8-OH-DPAT 1 9.30
CHEMBL49 BUSPIRONE 4.0 1 8.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL56 8-OH-DPAT Ki = 0.5 nM 9.30
CHEMBL49 BUSPIRONE Ki = 9.3 nM 8.03