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Assay Detail

CHEMBL616762

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against 5-HT1B serotonin receptor in rat striatum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Striatum
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1B (CHEMBL3459)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin.
Glennon RA, Titeler M, Lyon RA, Slusher RM.
J Med Chem (1988) 31 : 867 -870
PubMed 2965244 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.68 5.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8600 DOM 1 5.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8600 DOM Ki = 2070.0 nM 5.68