Assay Detail
Binding
CHEMBL616830
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Binding affinity was determined against 5-hydroxytryptamine 1C receptor was determined in male Sprague-Dawley rat brain.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.79 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 8.00 |
| CHEMBL275854 | — | — | 1 | 6.82 |
| CHEMBL266591 | — | — | 1 | 6.19 |
| CHEMBL268800 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39 | SEROTONIN | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL275854 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL266591 | — | Ki | = | 650.0 | nM | 6.19 |
| CHEMBL268800 | — | Ki | = | 690.0 | nM | 6.16 |