Assay Detail
Binding
CHEMBL616927
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Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.86 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL442 | ERGOTAMINE | 4.0 | 1 | 9.10 |
| CHEMBL7143 | — | — | 1 | 6.60 |
| CHEMBL267615 | — | — | 1 | 6.54 |
| CHEMBL7318 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL442 | ERGOTAMINE | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL7143 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL267615 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL7318 | — | Ki | = | 6225.0 | nM | 5.21 |