Assay Detail
Binding
CHEMBL617073
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Binding affinity against 5-hydroxytryptamine 2A receptor in humans
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2A ligands for PET or SPECT brain imaging.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.48 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | 2.0 | 1 | 9.52 |
| CHEMBL74355 | VOLINANSERIN | 3.0 | 1 | 9.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62919 | ALTANSERIN | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL74355 | VOLINANSERIN | Ki | = | 0.36 | nM | 9.44 |