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Assay Detail

CHEMBL617096

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for its agonist activity against human 5-hydroxytryptamine 1D receptor alpha for comparison purpose.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1D (CHEMBL1983)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.
Ismaiel AM, Dukat M, Law H, Kamboj R, Fan E, Lee DK, Mazzocco L, Buekschkens D, Teitler M, Pierson ME, Glennon RA.
J Med Chem (1997) 40 : 4415 -4419
PubMed 9435911 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.47 7.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL138958 1 7.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL138958 Ki = 34.0 nM 7.47