Assay Detail
Functional
CHEMBL617098
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its agonist activity against human recombinant 5-hydroxytryptamine 1D receptor alpha for comparison purpose.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.64 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140415 | — | — | 1 | 7.09 |
| CHEMBL140417 | — | — | 1 | 6.99 |
| CHEMBL138907 | — | — | 1 | 6.95 |
| CHEMBL136962 | — | — | 1 | 6.84 |
| CHEMBL140416 | — | — | 1 | 6.23 |
| CHEMBL136311 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140415 | — | Ki | = | 82.0 | nM | 7.09 |
| CHEMBL140417 | — | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL138907 | — | Ki | = | 112.0 | nM | 6.95 |
| CHEMBL136962 | — | Ki | = | 143.0 | nM | 6.84 |
| CHEMBL140416 | — | Ki | = | 590.0 | nM | 6.23 |
| CHEMBL136311 | — | Ki | = | 1800.0 | nM | 5.75 |