Assay Detail
Binding
CHEMBL617099
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability to displace [3H]-Ketanserin radioligand from porcine 5-hydroxytryptamine 2A receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2,4-Disubstituted pyrroles: synthesis, traceless linking and pharmacological investigations leading to the dopamine D4 receptor partial agonist FAUC 356.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.15 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57176 | — | — | 1 | 6.42 |
| CHEMBL56118 | — | — | 1 | 6.21 |
| CHEMBL2113718 | — | — | 1 | 6.07 |
| CHEMBL60815 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57176 | — | Ki | = | 380.0 | nM | 6.42 |
| CHEMBL56118 | — | Ki | = | 610.0 | nM | 6.21 |
| CHEMBL2113718 | — | Ki | = | 850.0 | nM | 6.07 |
| CHEMBL60815 | — | Ki | = | 1300.0 | nM | 5.89 |