Assay Detail
Binding
CHEMBL617171
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The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligand
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.66 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45491 | — | — | 2 | 9.24 |
| CHEMBL300647 | — | — | 2 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45491 | — | Ki | = | 0.57 | nM | 9.24 |
| CHEMBL300647 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL300647 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL45491 | — | Ki | = | 30.0 | nM | 7.52 |